Total IgE
Why Is This Test Done?
TOTAL IGE, SERUM-Introduction: The ImmunoCAP total IgE measures the total quantity of circulating IgE in human serum samples.
Test Utility:
• For allergy testing : IgE antibodies appear as a result of sensitization to allergens, and the measurement of circulating total IgE assists the clinical diagnosis of IgE-mediated allergic disorders. Elevated levels of circulating total IgE are usually seen in atopic eczema ,60% of patients with extrinsic asthma, and about 30% cases of hay fever.
• Parasitic diseases: Values may be elevated in ascariasis, visceral larva migrans, hookworm disease, schistosomiasis, echinococcus infestation).
• Diagnosis of monoclonal IgE myeloma.
• Diagnosis of bronchopulmonary aspergillosis.
• Total IgE may be decreased in hereditary deficiencies, acquired immunodeficiency, ataxia telangiaectasia & non-IgE myeloma.
Limitation:
A normal level of IgE does not eliminate the possibility of allergy, hence test is not recommended as a stand-alone screen. Value is influenced by type of allergen, duration of stimulation, presence of symptoms, hyposensitization treatment
Preparation Instructions
Fasting may be required. Follow the instructions on the booking screen.