EGFR (GLOMERULAR FILTRATION RATE, ESTIMATED)



Interpretation:  Glomerular filtration rate (GFR) is the best overall index of kidney function. Normal GFR varies according to age,sex, and body size,and declines with age. The National Kidney Foundation recommends using the CKD-EPI Creatinine Equation / Modification of Diet in Renal Disease equation (MDRD) to estimate GFR

Note

1. eGFR calculated using the 2009 CKD-EPI creatinine equation and GFR Category reported as per KDIGO guideline 2012

2. In patients, with eGFRcreat between 45-59 ml/min/1.73 m2 (G3a) and without any marker of kidney damage, it is recommended to measure eGFR with cystatin C for confirmation of CKD.

3. eGFR category G1 or G2 does not fulfil the criteria for CKD, in the absence of evidence of kidney damage

4. In a suspected case of Acute kidney injury (AKI), measurement of GFR should be done after 48-96 hours of any intervention or procedure.

5. GFR calculated by Serum Creatinine may be less accurate due to certain factors like Race, Muscle mass, Diet and certain Drugs. In such cases, eGFR should be calculated using Serum Cystatin C.