p-ANCA

ANTINEUTROPHIL CYTOPLASMIC AB(ANCA), SERUM-Anti-Neutrophilic Cytoplasmic Antibody testing is useful in the diagnosis and treatment of autoimmune mediated vasculitides. The diagnosis is made in correlation with the Clinical history , biopsy findings & ANCA positivity .Positive ANCA with cytoplasmic pattern (C - ANCA) is seen in the cases of Wegener''s Granulomatosis. The perinuclear pattern (P - ANCA) is seen in Polyarteritis Nodosa..The final diagnosis should be on the basis of criteria as given by the American College of Rheumatology Or by 2012 revised Chapel Hill consensus conference criteria.