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AMPA-GluR1 & R2
  • Overview

🧠 AMPA Receptor Antibody – GluR1 & GluR2 (IFA)

Test Code: AUTO14 (You can assign your internal code)
Method: Indirect Immunofluorescence Assay (IFA)
Sample Type: 🧫 CSF (preferred) or Blood (serum)
Reporting Time: ⏱ 10–14 days
Home Collection: ✅ Available


🔍 What This Test Detects:

The AMPA receptor antibody test detects autoantibodies against AMPA-type glutamate receptors (GluR1 and GluR2 subunits). These antibodies are linked with autoimmune encephalitis, a condition where the body attacks brain receptors.


🧬 Clinical Purpose:

Used to diagnose Autoimmune Limbic Encephalitis and other autoimmune neurological syndromes, especially in patients with:

  • Rapid-onset memory loss

  • Seizures

  • Personality changes

  • Sleep disturbances

  • Confusion or hallucinations


⚠️ When to Suspect:

  • Subacute memory impairment

  • Psychiatric symptoms (aggression, paranoia)

  • Temporal lobe epilepsy-like seizures

  • Suspected paraneoplastic encephalitis (esp. with lung, breast, or thymic tumors)


🧑‍⚕️ Clinical Usefulness:

  • Helps confirm antibody-mediated encephalitis

  • Often used alongside other tests: NMDA, GAD65, GABA-B, CASPR2

  • May help detect underlying cancers


Why Choose Speed Diagno?

  • NABL/CAP partnered labs for accurate IFA results

  • Home sample collection by certified phlebotomists

  • Quick booking through app or website

  • Expert guidance from our diagnostic team


🧠 Related Antibodies in Autoimmune Encephalitis Panel:

  • NMDA Receptor Antibody

  • GABA-B Receptor Antibody

  • LGI1 / CASPR2 Antibody

  • Anti-Hu, Anti-Yo, Anti-Ri

  • GAD65

All test groups and subgroup

  • AMPA-GluR1 & R2

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