Patient Preparation: No special preparation is required

Dengue NS1 Antigen Rapid Test Overview

Purpose: The Dengue NS1 Antigen Rapid Test is designed to detect the presence of the NS1 protein of the dengue virus in the blood. This protein is produced by the dengue virus during the early stages of infection, making this test useful for diagnosing dengue fever early on.

How It Works:

1.Sample Collection: A small blood sample is obtained, typically through a fingerstick or venipuncture.

2. Test Procedure:

   - The blood sample is added to the test device, which also includes a buffer solution.

   - The device contains specific antibodies that bind to the NS1 antigen if it is present in the sample.

   - A color change in the test lines on the device indicates the presence or absence of the NS1 antigen.

3.Result Interpretation:

   - Positive Result: Indicates that the NS1 antigen is detected, suggesting an active dengue virus infection. Further testing and clinical evaluation are recommended to confirm the diagnosis and determine the appropriate treatment.

   - Negative Result: Means that the NS1 antigen was not detected in the sample. This might suggest that the person does not have dengue or that the test was performed too early in the infection for the antigen to be detectable.

Timing:

- The test is most effective when performed in the early stages of the illness, typically within the first 5 days after the onset of symptoms. The ability to detect the NS1 antigen decreases as the infection progresses.

Limitations:

- False Negatives: A negative result does not completely rule out dengue infection, especially if tested later in the course of the illness.

- False Positives: Less common, but possible if the test cross-reacts with other similar viral antigens.

Advantages:

- Rapid and easy to perform.

- Provides results in about 15-20 minutes.

- Useful for early detection of dengue fever.

Follow-Up:

- Positive results should be confirmed with additional tests, such as dengue-specific antibody tests (IgM/IgG) or PCR, for a more comprehensive diagnosis.

- Clinical correlation with symptoms and travel history is important for accurate diagnosis and management.