Preparation: No special preparation or fasting required.

Procedure: A blood sample is drawn, usually from a vein in the arm.

The SCL-70 Antibody test detects antibodies against the SCL-70 protein, which is associated with systemic sclerosis (scleroderma), an autoimmune disorder that causes skin thickening and organ involvement. This test helps diagnose and assess the severity of scleroderma, particularly the diffuse form.