Urinary Calcium/Creatinine Ratio is a diagnostic test used to evaluate calcium excretion in the urine relative to creatinine levels. This ratio helps assess calcium metabolism and can aid in diagnosing various conditions related to calcium balance and kidney function.

Description:

• Purpose: The urinary calcium/creatinine ratio measures the amount of calcium in the urine relative to the amount of creatinine, a waste product. This helps in assessing calcium excretion and can be used to investigate conditions such as kidney stones, hyperparathyroidism, and metabolic bone diseases.

• Normal Range:

  • Generally, the normal range is between 0.1 and 0.3 (calcium/creatinine ratio) or 100-300 mg of calcium per gram of creatinine. However, normal ranges can vary depending on the laboratory and the method used.

• Why It’s Done:

  • To diagnose or monitor conditions affecting calcium metabolism.
  • To evaluate patients with calcium kidney stones or recurrent urinary tract infections.
  • To assess calcium balance in patients with disorders like hyperparathyroidism or vitamin D deficiency.Use a clean, sterile container for sample collection to avoid contamination.

Patient Preparation for Urinary Calcium/Creatinine Ratio Collection:

1. Sample Collection Instructions:

   • Timing: Usually, a spot urine sample is collected, but sometimes a 24-hour urine collection is required for more comprehensive assessment. A single spot sample should be collected at a consistent time of day, typically morning.
   • Hydration: Patients should be well-hydrated, but avoid excessive fluid intake right before the test to prevent dilution of the urine.
   • Avoid Contaminants: Use a clean, sterile container for sample collection to avoid contamination.

2. Medication and Diet:

   • Medications: Inform the healthcare provider of all medications and supplements, as some may affect calcium levels or kidney function.
   • Diet: Maintain a normal diet, but avoid excessive calcium intake or high doses of calcium supplements before the test, as these can influence results.

3. Activity:

   • Avoid vigorous exercise immediately before the test, as it may temporarily affect calcium excretion in the urine.

4. Instructions for Collection:

   • For a spot urine sample, collect the urine midstream to avoid contamination from the genital area.
   • For a 24-hour urine collection, follow specific instructions provided by the healthcare provider, typically involving starting and ending the collection at precise times and ensuring all urine is collected during the period.

Sample Collection:

• Spot Urine Sample: A single urine sample is collected in a sterile container.
• 24-Hour Urine Collection: Collect all urine produced over a 24-hour period in a special container provided by the healthcare provider.

The urinary calcium/creatinine ratio helps in diagnosing and managing conditions related to calcium metabolism and kidney function.